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Description

In another embodiment, a method is provided for a one-step synthesis comprising reacting a reducing agent (e.g., lipoic acid) with a halogenated choline (e.g., bromocholine bromide) to yield a choline ester

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In the 1940s and 1950s, high-dose folic acid was used to reverse the megaloblastic anemia of B12 deficiency, but that treatment masked the underlying deficiency and possibly worsened its neurological progression

Protein expression was detected by SuperSignal West Pico Chemiluminescent substrate (Thermo, Waltham, MA, USA) and Fujifilm LAS-3000 (Fujifilm, Tokyo, Japan)