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Participants took either an SSRI, 1000 mg of citicoline, or 600 mg of choline alfoscerate daily for six months

In this context, ammonia-lowering agents target impaired nitrogen metabolism, nutritional optimization and branched-chain amino acid (BCAA) supplementation address sarcopenia and metabolic imbalance, and microbiome-directed therapies aim to correct dysbiosis, which contributes to CHE pathogenesis

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It is supported by a strong clinical evidence base

doi: 10.1007/s13213-015-1167-1 67 KaraiZ.Ban.MacherouxP

Improved Insulin Sensitivity Early research suggests potential support for healthy blood sugar metabolism