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Pamrevlumab, an Anti-connective Tissue Growth Factor Therapy, for Idiopathic Pulmonary Fibrosis (PRAISE): a Phase 2, Randomised, Double-Blind, Placebo-Controlled Trial

Following binding to TFRC, the TF-TFRC complex is internalized via receptor-mediated endocytosis

22 In addition, PHLDA1 was highly expressed in ovarian cancer patients, and silencing of PHLDA1 could promote the death of human ovarian cancer cells

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RNA knockdown Knockdown of gene expression in HaCat cells was achieved by transfection of siRNAs against ATM, KEAP1, BRCA1 or Scrambled siRNA with Oligofectamine (Life Technologies) in accordance with the manufacturers instructions ( Online Supplementary Appendix and Online Supplementary Table S4 )