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Its function as physiological secondary messengers in signal transduction becoming increasingly apparent

NSAIDs become protonated when they come into contact with acidic stomach juice (pH 2), which allows them to pass lipid membranes and enter epithelial cells (pH 7.4) without ionizing [17]

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New Phytol 180:434441 Talukdar D (2013)Arsenic-induced oxidative stress in the common bean legume, Phaseolus vulgaris L

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Bourke SL, Schlag AK, OSullivan SE, Nutt DJ, Finn DP