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Several studies have shown that anti-EpCAM antibodies limit therapeutic efficacies as the results of showing dose- and target-dependent in metastatic cancers, short serum half-life, altered EpCAM expression pattern, and differential cleavage and localization of EpICD in cancer cells (Fig

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Expanding therapeutic access must be matched by access to pharmaceutical-quality APIs supported by appropriate quality systems, manufacturing controls, analytical testing, documentation, and traceability