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The cell death induced by the B2M-ADC does not seem to be led by apoptosis but rather by necrosis 49

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Tryptophan degradation occurs primarily through light-induced oxidation

This can contribute to improvements in cognition, mood, and anxiety symptoms

It provides a model for investigating how a simple molecule can act as a master regulator, influencing multiple interconnected pathways to shift the overall state of a cell or tissue culture