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Antioxidant systems play a crucial role in preventing peroxidative damage by scavenging free radicals or indirectly consuming compounds that induce free radical generation, thus preventing ferroptosis

CO exerts an anti-inflammatory effect by inhibiting IB (IKK) kinase activity, thereby stabilizing IB and preventing NFB from translocating to the nucleus, which reduces the transcriptional priming of NLRP3 and pro-inflammatory cytokines

Kubiszeski EH, de Medeiros SF, da Silva Seidel JA, Barbosa JS, Galera MF, Galera BB (2015) Glutathione S-transferase M1 and T1 gene polymorphisms in Brazilian women with endometriosis

Concurrently, MI increases adiponectin while reducing leptin and resistin, improving adipose redox balance and normalizing gonadotropin-androgen output (237)

Hinz B, Phan SH, Thannickal VJ, Prunotto M, Desmouliere A, Varga J, De Wever O, Mareel M, Gabbiani G (2012) Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

Finally, we critically evaluate current translational challenges and present future perspectives on addressing multifaceted disease pathologies using Pt nanozymes