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Figure 5 shows the points that can be measured by biochemical assays, a list of which is provided in the Supplementary Information (Table S1)

Oncogene 36, 29002909

However, therapeutic approaches such as immune checkpoint blockade (ICB), adoptive cell transfer (ACT), cytokine-based immunotherapy, or combination therapies often fail to achieve desired clinical effects due to the immunosuppressive tumor microenvironment (TME) [5]