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LepR GHR KO mice also showed decreased adiposity, although no differences in food intake and energy expenditure were observed in this model

Consistent with the reduced bacterial burden, gross pathology revealed fewer granulomatous lesions in the lungs of animals infected with the metZ than those infected with the Rv-WT and complement strains at 8 weeks p.i

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Axin2 expression measurement using the same set of samples