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CYP 450 Families and subfamilies Foye's principles of medicinal chemistry CYP Biotransformations Chemically diverse small molecules are converted, generally to more polar compounds Reactions include: Aliphatic hydroxylation, aromatic hydroxylation Dealkylation (N-,O-, S-) N-oxidation, S-oxidation Deamination Dehalogenation Oxidative Phase-I involving cytochrome P-450 enzymes: Aliphatic hydroxylation: Mainly occur on the ultimate () or penultimate (-1) carbon atom in the structure

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In addition to the above antimicrobial and antifungal effects, polyphenol extracts from mung bean sprouts have also been shown to have activity against Helicobacter pylori , one of the most common bacterial infections in human beings causing gastroduodenal disease [6]

186 These findings shed light on the mechanism of lactylation in immunosuppression, metabolic reprogramming, and chemoradiotherapy resistance in GBM, suggesting that targeting glycolysis-derived lactylation could be a potential combined therapeutic strategy for GBM

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