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Sep 2020;8(5):1184-1193

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Systematic review of human and animal studies examining the efficacy and safety of N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) in traumatic brain injury: impact on neurofunctional outcome and biomarkers of oxidative stress and inflammation

doi: 10.1093/femsyr/foad045, PMID: [DOI] [PubMed] [Google Scholar] Vishwakarma M H

Similar results were obtained in DSS-induced colitis mice, as 4-methyl-esculetin administered orally at 25 mg/kg daily, improved microscopic parameters, reduced MPO activity, lowered colonic IL-6 levels, and prevented GSH depletion compared to the DSS-control group [562]