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As monotherapy , a multicentre, randomised, double-blind, placebo-controlled and active-controlled Phase 2 dose-finding trial enrolled 706 adults with overweight or obesity (without diabetes) to once-weekly subcutaneous cagrilintide across doses of 0.3 to 4.5 mg over 26 weeks

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Representative research domains include: In vitro skin and connective tissue models examining fibroblast activity, ECM deposition, collagen organization, and responses to oxidative stress

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You should always start on the lowest dose and titrate upward based on three key factors: 1