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Investigations into epigenetic interventions, particularly DNA demethylation, have included the use of 5-azacytidine and 5-azadeoxycytidine (221)

Cell (2022) 185(14):240121

It also discusses the possible involvement of the retina and molecular biomarkers, specifically Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) and ciliary neurotrophic factor (CNTF) in the pathophysiology of SSD and ASD

However, during the onset and progression of autoimmune diseases, immune cells and parenchymal cells in target organs may undergo various types of programmed cell death, including pyroptosis, autophagy, necrosis, and apoptosis

Int J nanomed (2021) 16:103750

Therefore, it is important to characterize the entire chain of the molecular events linking ocular hypertension and RGCs death in order to find the most sensitive and convenient target(s) for neuroprotective therapeutic intervention