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Ocular vascular dysregulation is another pathological feature of glaucoma, the underlying mechanism of which remains unclear

The charge is distributed equally over the two non-bridging oxygen atoms

IMP, inner membrane protein

The decrease in insulin action known as insulin resistance is caused by several factors, including direct deleterious effects of excess lipids and other metabolic fuels on organs and tissues, enhanced inflammatory signalling, and activation of endoplasmic reticulum (ER) stress pathways