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This suggests that multiple tissues might participate in the oxidation TMA to TMAO

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As a result, senescent microglia secrete a range of SASP components, IL-6, IL-8, MMP3, MMP12, CXCL1, CXCL2, and CXCL10 (Cook et al., 2022)

ix) enantiospecific synthesis from non-racemic precursorsa synthetic technique whereby the desired enantiomer is obtained from non-chiral starting materials and where the stereochemical integrity is not or is only minimally compromised over the course of the synthesis