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These methyl groups regulate the enzymes and factors essential for producing tetrahydrobiopterin (BH4), a key cofactor required for synthesizing monoamine neurotransmitters from amino acids

Secondary iron overload in -thalassemia patients is commonly caused by increased dietary iron absorption and can be a result of multiple blood transfusions [3]

Food and Drug administration (2019)

Vitamin D supplementation, particularly in neoadjuvant settings, has demonstrated improvements in pathological complete response (pCR) rates in breast cancer patients, although effects on axillary pCR remain inconclusive (349)

Nature 460 , 352358 (2009)