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Consistent with this notion, under conditions of cysteine starvation, the GSH-catabolizing enzyme CHAC1 mobilizes cysteine to sustain mitochondrial Fe-S cluster biogenesis and respiratory function

Chronic Hepatitis B infection in children and its relation to pulmonary function tests: a case-control study

J.BickelC.SchnabelR.Genth-ZotzS.TorzewskiM.et al

During this reaction, glutathione is converted into oxidized disulfide glutathione (GSSG), which is recycled back to two molecules of glutathione by GSSG reductase at the expense of NADPH/H+, thus forming what is known a redox cycle (Fig

doi: 10.1016/j.tibs.2013.01.004 67 JiangZ.LinJ.DongH.ZhengX.MarjaniS

The complex results of scavenger receptor deletion should not be surprising given that scavenger receptors have multiple ligands and that an important role of scavenger receptors expressed by macrophages is to allow these macrophages to remove bacteria and damaged cells from surrounding tissues