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second, GrxSSG binds GSH and the glutathionyl moiety is removed regenerating Grx and producing GSSG

More help Oxidation of Reduced Glutathione Leading to Mortality The current version of the Developer's Handbook will be automatically populated into the Handbook Version field when a new AOP page is created.Authors have the option to switch to a newer (but not older) Handbook version any time thereafter

Hence, molecules that protect and revitalize mitochondria could recreate a juvenile state of protection against free radicals (Figure 5) [36]

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Conflict of interest Author MB was employed by the company Navita S.r.l., while authors AS, FC and VG were consultants of Navita S.r.l

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