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3 When there is reduced elimination, or production is increased, ammonia accumulates and is shunted to the systemic circulation resulting in brain accumulation and subsequent dysfunction

This chain reaction progresses until two lipid peroxyl radicals react, thus terminating the process

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"High Prevalence of Vitamin D Inadequacy and Implications for Health." Mayo Clin Proc 81.3 (2006): 353-73

O cido alfa-lipoico (AAL) DEVE SER CONSIDERADO no tratamento da NPD leve a moderada, para uso no longo prazo, visando melhora da fora muscular e estabilizao do dficit neuroptico, considerando sua segurana e custo-benefcio

ARC, arcuate nucleus of the hypothalamus