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Additionally, GSH or GSSG are potential candidate ligands of NMDA receptors (NMDARs) because the constituent amino acid sequence bears a close structural resemblance to those of NMDAR activators 59

4.1.5 Paraoxonase 1 Paraoxonase 1 (PON1) is a calcium-dependent esterase primarily associated with high-density lipoprotein (HDL), where it plays a crucial role in reducing OS by hydrolyzing lipid peroxides and preventing low-density lipoprotein (LDL) oxidation (Figure 4)

[10] The logic: if the peptide declines with age and its gene expression profile favors tissue repair, restoration of youthful levels might restore youthful repair capacity

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In this context, the added metabolic stress of high GH levels is much more likely to tip the scales and exacerbate the underlying problem

The EHC monographs have become widely established, used and recognized throughout the world