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On the other hand, activation of CD38 in immune cells appeared to increase cytokine release and cellular migration toward sites of inflammation, suggesting important roles in the regulation of adaptive immune responses 51,52

In general, these findings suggested that ZFPG + US treatment effectively disrupted the glycolysis process, reduced intracellular GSH levels, and enhanced intracellular oxidative stress of androgen-dependent and -independent prostate cancer cells, thereby universally inducing immunogenic ferroptosis of prostate cancer cells and stimulating the immune response of the body