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Helps improve elasticity and strengthen the skin barrier

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Upon release by the endothelium, NO stimulates the soluble guanylate cyclase (sGC) in vascular muscle cells, leading to a rise in the intracellular concentration of cyclic guanosine 3,5-monophosphate (cGMP) and relaxation

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Of these 71 patients, 35, 23, and 13 were diagnosed with MPA, GPA, and EGPA, respectively