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Sinn DH, Kang D, Kang M, Guallar E, Hong YS, Lee KH, et al

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Suramin, a century-old drug used to treat African sleeping sickness and river blindness, can effectively inhibit SARS-CoV-2 polymerase activity with at least 20-fold more activity than RDV-3Pi in biochemical assays and inhibits viral replication in vitro 141

72 h post supernatant transfer, cells were lysed to analyse replication in infected cells

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14,15 On the other hand, in a recent study by Parkinson at al., lysine is found to be much more abundant in the human skin proteome than cysteine