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These side effects limit the dose that can be administered, reducing drug efficiency, primarily because most anti-neoplastic agents are rapidly metabolized and eliminated from the body 3,4

[DOI] [PubMed] [Google Scholar] 54.Rochon J, Protiva P, Seeff LB, Fontana RJ, Liangpunsakul S, Watkins PB, Davern T, McHutchison JG Drug-Induced Liver Injury Network (DILIN) Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury