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Through these mechanisms, HSP70 and HSP90 reduce the formation of neurofibrillary tangles, thereby mitigating one of the core pathological processes underlying tau-mediated neurodegeneration

These data suggest that increased GSH levels should have a positive effect on BP in hypertension, and we propose that pathological inhibition of vascular relaxation involves not only NO production by endothelial cells but also glutathione-dependent bioavailability of NO, with S-nitrosothiols playing an important role in the pathway

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Efforts have also been made to express disulfide-rich proteins into the cytoplasm with some success by removing several proteins that balance the redox potential in the cytoplasm of E

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