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Canagliflozin, a sodium glucose cotransporter 2 inhibitor, attenuates obesity-induced inflammation in the nodose ganglion, hypothalamus, and skeletal muscle of mice

A common structure is 4 weeks activation + 4 weeks consolidation + 24 weeks maintenance a 1012 week on-cycle, followed by a 48 week break before repeating

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[2] The decline of GH results in reduced production of insulin-like growth factor (IGF-1), which typically works in tandem to manage and modulate our fat, protein, and glucose metabolism