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PPs could decrease AFs-associated oxidative stress, genotoxic, mutagenic, and carcinogenic effects by improving cellular antioxidant balance, regulation of signaling pathways, alleviating inflammatory responses, and modification of gene expression profile in a dose/time-reliant fashion

Recent work suggests that peritoneal fluidderived exosomal miR-493 reduces paclitaxel sensitivity by downregulating MAD2L1, further supporting the notion that treatment failure in peritoneal metastasis is often governed by microenvironment-shaped resistance networks (105)

A previous study by Salem et al

Instead, it specifically targets adipose tissue metabolism through alternative pathways

Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy