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doi: 10.1016/s0891-5849(02)00794-3

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ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 -mutant lung cancer

For example, a 2020 study found: Genetic predisposition to elevated serum IGF-1 levels was associated with higher risk of type 2 diabetes and coronary artery disease. The researchers note: Abnormal serum IGF-1 levels are associated with an increased risk of type 2 diabetes and cardiovascular diseasethe role of IGF-1 levels within the normal range in cardiometabolic disease remains unclear. 4

El Basuini MF, Hussein AT, El-Hais AM, Elhetawy AIG, Soliman AA, Gabr SA, Abu-Elala NM, Luo Z, Zaineldin AI, Teiba II, El-Serafy RS, El-Ratel IT, Gewaily MS, El-Bilawy EH, Mamdouh I, Shehata AI (2025) Impacts of dietary Ajwain (Trachyspermum ammi L.) on growth, antioxidative capacity, immune responses, and intestinal histology of grey mullet (Liza ramada)