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Drug Target Insights

Mitochondrial lipid peroxidation was determined using the ratiometric fluorescent probe MitoPerOX (Cayman Chemical, 18798) according to the manufacturers protocol

However, it is important to note that while the high energy demand theory is widely accepted, in vivo evidence directly confirming it as the primary or sole cause of neuronal loss in PD remains incomplete, as other factors such as calcium dyshomeostasis and iron metabolism abnormalities are also intertwined [20, 21]

Thus, Quer, as an activator of the GSH system, is a promising natural small molecule for the treatment of cardiac injury

Imaging biomarkers in neurodegeneration: current and future practices