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Listed among some of the more severe indicators of a B12 deficiency are cognitive disorders, depression, paranoia or even a loss of the senses of taste and smell

However, its use as an effective oral supplement has been limited due to poor absorption when taken traditionally

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Recombinant FcRn Truncated soluble and Glutathione S-transferase (GST) tagged human FcRn lacking the transmembrane domain (hFcRn-GST) was produced in HEK293E cells and purified on a GSTrap column (Cytiva Life Sciences) 67