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Various noninfectious inflammatory ailments such as acute pancreatitis are characterized by high mortality and morbidity, and accompanied by tissue necrosis and severe inflammation

Blood 98 : 30663073 Li P, Nijhawan D, Budihardjo I, Srinivasula S, Ahmad M, Alnemri AS and Wang X (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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