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Neuropeptides 45(1):3342

Mining microbes for mental health: determining the role of microbial metabolic pathways in human brain health and disease

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As a reference, recombinant IGF-1 injections have a half-life of under 6 hours when given subcutaneously as a treatment of growth failure and slower development of children due to poor IGF-1 levels

3a), and renders the synthesis of cysteine dependent on the activity of one-carbon metabolism (methionine and folate cycles)