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Six 5-week-old female BALB/c mice bearing tumors were randomly assigned into two groups

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In addition, a clinical study applying coenzyme Q10, a mitochondrial antioxidant, did not demonstrate clinical efficacy in patients with early PD [135]

Cancer Risk A review and discussion stated: ROS production is significantly increased in cancer cells because of mitochondrial dysfunction, altered metabolism, and frequent genetic mutations, resulting in an accumulation of large amounts of oxidized protein, DNA, and lipids as an adaptive response, cancer cells harbor elevated levels of ROS-scavenging molecules

Zinc finger E-box binding homeobox 1 (ZEB1) is a crucial molecule involved in the EMT

Many studies reported iron-binding properties of monomeric frataxin proteins (Campbell et al., 2021)