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However, it is now widely accepted that oxidative stress, defined as an imbalance between reactive oxygen species (ROS) and antioxidants, may be implicated in the pathophysiology of endometriosis causing a general inflammatory response Key Points Lay Summary Biomarkers as a Diagnostic Tool By Kasthuri Nair Ahn, Singh and Tayade discuss the difficulties and delay in diagnosing Endometriosis in their paper titled Biomarkers in endometriosis: challenges and opportunities. Thus far research has identified a multitude of potential biomarkers that are found in various parts of the Key Points Lay Summary Endometriosis : A Whole Body Disease By Kasthuri Nair Endometriosis is a disease that impacts multiple parts of an individuals body