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Alpha-Synuclein Toxicity on Protein Quality Control, Mitochondria and Endoplasmic Reticulum

3.3.1 Drug treatment strategy Published guidelines identify airway clearance as a critical treatment for bronchiectasis, although the supporting evidence remains relatively weak (83, 84, 93)

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Presenting a quinoxaline framework, the chemical structure of brimonidine manifests a secondary amine linker attached at the 3-position to a dihydroimidazole functionality

also developed mPEG-SS-PZLL nanomicelles for DOX delivery, with a lower loading efficiency of 16.7 wt%, good sensitivity to GSH, and high cytotoxicity towards MCF-7 cancer cells [111]