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Stretch marks are common skin concerns that develop when the skin stretches or shrinks too quickly, often from pregnancy, weight changes, or growth spurts, leaving visible streaks on areas like the abdomen, thighs, or arms

Safety and efficacy of ampreloxetine in symptomatic neurogenic orthostatic hypotension: a phase 2 trial

10.1038/onc.2017.11 Oncogene 9 BrintonL

There have also been reports that some plant extracts used in traditional or indigenous medicine, such as those of American herb Eriodictyon angustifolium or the Chinese plant Polygonum multiflorum can slow greying, and re-pigmentation has even been observed in response to injuries to the scalp during skin cancer surgery

So, the prognosis varies according to these types 6

In situations characterized by inflammation, specific cytokines, notably TNF-, IL-6, and IL-1, amplify leptin production by acting as potent stimulants for adipocyte activity