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Long-term hyperglycemia in diabetic patients accelerates the glycosylation reaction, leading to the accumulation of AGEs in blood vessels, nerves and kidneys, which can lead to diabetic complications (such as diabetic nephropathy, retinopathy and neuropathy)

For phBEC, only the basolateral supernatant was analysed, as no GPX3 was detected in the apical supernatant

NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

Animal experiments have shown that RIPC can protect the spinal cord from I/R injury

To test how well it works in diabetic rats with long-lasting wounds caused by infections, oval wounds (8 6 mm) were made on the upper paws of the rats, infected with Staphylococcus aureus, and treated for about 20 days

According to the classic step-up approach, treatment with 5-aminosalicylic acid compounds is the first step in the treatment of mild to moderately active UC