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Any fraction that is not conjugated, then undergoes CYP 450 metabolic pathway being converted to cytotoxic metabolite, N-acetyl-p-benzoquinone-imine (NAPQI)

In these studies, odevixibat treatment reduced serum bile acids and improved pruritus

5.3 The intervention of antibiotics In several studies of uveitis models, raising mice under germ-free conditions or depleting the gut microbiome with antibiotics significantly reduced the severity of the disease (36, 102, 107, 108)

These may include slight headache, mild dizziness, or minor nasal irritation

230 Resveratrol Resveratrol (Figure 9) is a naturally occurring polyphenolic compound which is extensively present in grapes, red wine, and peanuts

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