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Endothelial cells express ICAM-1, VCAM-1, E-selectin, and P-selectin involved in leukocyte recruitment and platelet adhesion during thrombosis and inflammation and contribute to early phases of atherosclerosis

Often called the bodys master antioxidant, glutathione plays a central role in neutralizing free radicals, supporting detoxification, and maintaining cellular health

However, the precise mechanisms of ferroptosis in CHD have not been fully elucidated, necessitating further in-depth mechanistic investigations and the development of more effective and safer clinical intervention strategies to ultimately improve patient outcomes

doi: 10.1080/24750573.2018.1517466 21 OkuyucuMCeylanMFTural HesapciogluSKonyaliogluFSFirat OguzENeseliogluS