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Description

Together, these data indicate that, in SZ, suppressed autophagic function is associated with elevated inflammatory response

Simultaneous binding of GSH to R1198, K333, H336, Y441 and R1250 (GSH binding to the P-pocket) or W554, R594, Y1244 and R1250 (GSH binding to H-pocket) would bridge TMD1 and TMD2 in both cases