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The aberrant activity of these enzymes is closely linked with the pathogenesis of a wide range of diseases, not only cancers but also metabolic, inflammatory, and neurological disorders, underscoring the therapeutic relevance of targeting these pathways

A.|Sethi, K.|Caviness, J

7.4 Therapeutic potential of microglial regeneration Furthermore, microglial regeneration as a therapeutic approach holds significant promise, with adult brain-resident nestin-positive progenitor cells capable of rapidly proliferating and differentiating into ramified microglia under CSF1R signaling