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Therefore, researchers aim to target AR using aldose reductase inhibitors (ARIs), which can be found in natural products (nutraceuticals) such as ginger

For each recording (15 laser stimulations), the cerebral blood flow (CBV) was normalized into a relative steady-state value (rCBV) and calculated as the following: rCBV = (CBV(t) - CBV 0 )/CBV 0 , where CBV(t) is the power doppler value t seconds after the start of laser sequence, and CBV 0 is the baseline in the ROI

A single dose of 6 (100 mg/kg i.p.) at 42 d.p.i

In addition, the intestinal microbiota, dietary fiber and fat, various antioxidants, pH regulation, and low-temperature extraction methods can increase the bioavailability of PCs

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These results were further replicated in different cancer cell lines (Supplementary Fig