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Description

Journal of Clinical Endocrinology & Metabolism

Structures were solved by molecular replacement using Phaser-MR and chain A of PDB 6U32 as the model

EGCG-Zn treatment significantly downregulated the expression of multiple key proinflammatory genes in the MAPK pathway (such as Fos, Jun, and Mapk8), suggesting that it could alleviate radiation-induced tissue injury by inhibiting MAPK-mediated inflammatory amplification and apoptotic signaling