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Individuals suffering with gout are at greater risk for depression, especially those with active flares and untreated gout

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doi: 10.1016/j.cmet.2018.02.024 109 FeuererMHerreroLCipollettaDNaazAWongJNayerAet al

The above studies have fully demonstrated the positive effect of SCFA in fighting inflammation, but butyrate also seems to have a negative effect, inducing differentiation and apoptosis in transformed cells