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There is clear evidence for the use of B12 in diabetic neuropathy, either alone or with other treatments, and in lowering homocysteine levels, again either alone or with other nutrients

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Less common adverse effects include hypersensitivity reactions, including anaphylaxis, and exacerbation of acne vulgaris

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It is important to note that the treatment plan will vary depending on the individual and the underlying cause of the pernicious anemia