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doi:10.3390/ijms20010231

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Firstly the Review was based on research papers that were very suspect and involved groups of individuals that did not represent a wide cross section of society (the primary study was of mainly elderly males)

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However, the effect of supplementation on folic acid serum concentrations differed between the NW and EBW groups, with a more pronounced increase observed in the NW group compared to the EBW group

The S 1 PESs for each antimetabolite contain two energy minima, one being the metal-to-ligand charge transfer (MLCT) and another the ligand- eld (LF) state