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Description

To determine whether combined inhibition of GGCT and xCT results in synergistic effects, we treated cells with pro-GA and erastin at a fixed ratio for 3 days

pylori in Cth / BMmacs (Figure 8, B and C)

In addition to KRAS G13C , we also investigated the reactivities towards KRAS G12C 1169 (Cys-light) and KRAS wt 1169 , where no to very low modification was observed, indicating good overall selectivity towards Cys13 (Figure S1)