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287 Consistent with this, upon VDR siRNA knockdown, the downregulation of TJ proteins, including CLDN1, ZO-1/2, and E-cadherin, and the reduction of TER were revealed, which were relieved by 1,25-dihydroxyvitamin D3 [1,25(OH) 2 D 3 ], suggesting the role of VDR-mediated vitamin D signaling in the regulation of TJs

Neurochem Res 42 , 16611675 (2017)

doi:10.3171/2010.4.JNS10118 18

For instance, magneto-sensitive iron oxide has been incorporated into PEG-solid LNPs 170 , enabling external magnetic guidance to physically pull particles through highly viscous airway mucus and enhance their contact with the epithelium

Dysbiosis-induced oxidative stress disrupts the intricate equilibrium of gut homeostasis, leading to an increased degree of immunological dysregulation (Pellon et al., 2021)

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