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Some have called for the FDA to reconsider its recommendations, but no changes made to date

The loading phase typically uses 2-2.5mg twice weekly for 4-6 weeks, totaling 4-5mg per week

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After washing three times with PBS, fluorescence-conjugated secondary antibodies were added to the sections, which were incubated with secondary antibodies for 1 h at room temperature

2002;249(Suppl 2):II259

Importantly, NUPR1 is lost in IPF and IPF-derived epithelial cells were significantly more sensitive to NUPR1 inhibition, suggesting that loss of NUPR1-mediated survival mechanisms in the IPF airway epithelium may contribute to disease pathogenesis