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Future medicinal chemistry efforts may yield next-generation compounds with enhanced properties, including improved tissue selectivity, modified pharmacokinetics, or additional mechanistic activities that complement NNMT inhibition

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The measurements were performed three times consecutively without adjusting the position of the rats, and the average MBR was calculated accordingly

Morpho-dynamic changes of mitochondria during ageing of human endothelial cells

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

The astrocytic response to the dopaminergic denervation of the striatum